Publications


Human fallopian tube-on-a-chip for preclinical testing of non-hormonal contraceptives with living human sperm


A. Stejskalová, K. Calderon, M. Collins, Jessica F. Feitor, Debraj Ghose, Shiyan Tang, O. Gutzeit, N. Badey, Aakanksha Gulati, María V. López, David B. Chou, J. Petrozza, R. Plebani, A. Junaid, Bogdan Budnik, Donald E. Ingber

bioRxiv, 2026


Human inflammatory bowel disease-on-a-chip for modelling disease progression, cancer initiation and sex-specific effects.


Alican Ozkan, G. Merry, David B. Chou, Ryan R. Posey, A. Stejskalová, K. Calderon, M. Sperry, Joshua Piatok, Viktor Horváth, Lorenzo E. Ferri, Emanuela Carlotti, S. McDonald, Douglas J. Winton, R. Ricciardi, Liliana G. Bordeianou, Sean R. R. Hall, Girija Goyal, Donald E. Ingber

Nature Biomedical Engineering, 2026


Cervical mucus in linked human Cervix and Vagina Chips modulates vaginal dysbiosis


O. Gutzeit, Aakanksha Gulati, Z. Izadifar, A. Stejskalová, Hassan Rhbiny, Justin Cotton, Bogdan Budnik, S. Shahriar, Girija Goyal, A. Junaid, Donald E. Ingber

npj Women's Health, 2025


Human Cervix Chip: A Preclinical Model for Studying the Role of the Cervical Mucosa and Microbiome in Female Reproductive Health


Z. Izadifar, A. Stejskalová, Aakanksha Gulati, O. Gutzeit, D. Ingber

Bioessays, 2025


Induction of cervical dysfunction associated with preterm birth by IL-1 and dysbiotic microbiome revealed in human endocervix chips


A. Stejskalová, K. Calderon, David B. Chou, Aakanksha Gulati, Jessica F. Feitor, Z. Izadifar, O. Gutzeit, Yasmine Bouchibti, Siyu Chen, R. Plebani, Justin Cotton, J. Hughes, Thomas Ferrante, Bogdan Budnik, Girija Goyal, A. Junaid, C. Lebrilla, D. Ingber

bioRxiv, 2025


O-295 Analysis of human sperm behavior and assessment of non-hormonal contraceptive efficacy in a human cervix chip


S. Tang, N. Badey, M. Collins, A. Stejskalová, A. Gulati, K. Calderon, O. Gutzeit, A. Junaid, D. Ingber

Human Reproduction, 2025


Synergistic therapeutic effects of endolysin BNT331 and a Lactobacillus crispatus consortium in a human vagina chip model of bacterial vaginosis


Aakanksha Gulati, Alicia Jorgenson, Ashleigh M. Williams, Hassan Rhbiny, Lenka Podpera Tisakova, Lorenzo Corsini, Mahya Fazel-Zarandi, Jiawu Xu, J. Elsherbini, O. Gutzeit, A. Stejskalová, Nina LoGrande, Briah Cooley Demidkina, Yuncheng Man, Girija Goyal, D. Kwon, C. M. Mitchell, A. Junaid, Donald E. Ingber

bioRxiv, 2025


Mucus production, host-microbiome interactions, hormone sensitivity, and innate immune responses modeled in human cervix chips


Z. Izadifar, Justin Cotton, Siyu Chen, Viktor Horváth, A. Stejskalová, Aakanksha Gulati, Nina LoGrande, Bogdan Budnik, S. Shahriar, Erin R. Doherty, Yixuan Xie, Tania To, S. Gilpin, A. Sesay, Girija Goyal, C. Lebrilla, Donald E. Ingber

Nature Communications, 2024


Modeling mucus physiology and pathophysiology in human organs-on-chips.


Z. Izadifar, Alexandra Sontheimer-Phelps, Bob A. Lubamba, H. Bai, Cicely Fadel, A. Stejskalová, A. Ozkan, Queeny Dasgupta, Amir Bein, A. Junaid, Aakanksha Gulati, G. Mahajan, S. Kim, Nina LoGrande, Arash Naziripour, D. Ingber

Advanced Drug Delivery Reviews, 2022


Collagen I triggers directional migration, invasion and matrix remodeling of stroma cells in a 3D spheroid model of endometriosis


A. Stejskalová, V. Fincke, M. Nowak, Yvonne Schmidt, K. Borrmann, Marie-Kristin von Wahlde, S. Schäfer, L. Kiesel, B. Greve, M. Gotte

Scientific Reports, 2021


In vitro modelling of the physiological and diseased female reproductive system.


A. Stejskalová, H. Vankelecom, M. Sourouni, Magdalene Y. Ho, M. Gotte, B. Almquist

Acta Biomaterialia, 2021


The ellagic acid metabolites urolithin A and B differentially affect growth, adhesion, motility, and invasion of endometriotic cells in vitro.


B. M. Mc Cormack, N. Maenhoudt, V. Fincke, A. Stejskalová, B. Greve, L. Kiesel, G. Meresman, H. Vankelecom, M. Götte, R. Barañao

Human Reproduction, 2021


Biologically Inspired, Cell-Selective Release of Aptamer-Trapped Growth Factors by Traction Forces


A. Stejskalová, N. Oliva, Frances J. England, B. Almquist

Advances in Materials, 2019


A Physicochemically Optimized and Neuroconductive Biphasic Nerve Guidance Conduit for Peripheral Nerve Repair


A. Ryan, W. Lackington, A. Hibbitts, A. Matheson, T. Alekseeva, A. Stejskalová, Phoebe Roche, F. O’Brien

Advanced Healthcare Materials, 2017


Using biomaterials to rewire the process of wound repair


A. Stejskalová, B. Almquist

Biomaterials Science, 2017


Programmable biomaterials for dynamic and responsive drug delivery


A. Stejskalová, M. Kiani, B. Almquist

Experimental biology and medicine, 2016